Watch the best plays by San Francisco 49ers running back Christian McCaffrey from his 2-TD game during Week 9 of the 2025 NFL season.

McCaffrey ran for a three-yard score to put the 49ers up on the Giants 34-17 with 4:13 left to play and that gave him 16 career games with both a rushing and a receiving score. That broke a tie with Marshall Faulk for the most in NFL history.

The SportsLine Machine Learning Model AI has locked in its top Week 9 NFL prop picks for players like Christian McCaffrey, Ja'Marr Chase and Justin Herbert

San Francisco 49ers running back Christian McCaffrey takes the toss sweep for a 16-yard surge. Indianapolis Colts defensive end Laiatu Latu lassos Pittsburgh Steelers quarterback Aaron Rodgers for a 7-yard sack.

In Week 9, Christian McCaffrey and the San Francisco 49ers go head to head against the New York Giants at 1 p.m. ET on Sunday at MetLife Stadium. McCaffrey, in his last game, posted this statline: 8 carries, 25 yards; 3 receptions, 43 yards.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 9 on a sizzling 45-28 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Christian McCaffrey and Jim Harbaugh headline the list of nominees that have been selected as potential winners of the NFL's Salute to Service Award.

Oct 26, 2025; Houston, Texas, USA; San Francisco 49ers running back Christian McCaffrey (23) runs after a handoff from San Francisco 49ers quarterback Mac Jones (10) during the first quarter against the Houston Texans at NRG Stadium. Mandatory Credit: Troy Taormina-Imagn Images / Troy Taormina-Imagn Images