The controlled activation of cell death pathways triggers an acute, transient inflammatory response that, combined with the efficient phagocytosis of dead cells, ultimately restores tissue homeostasis ...

Understanding inflammation—and, above all, how to regulate it—is one of the great medical challenges of modern medicine. Its ...

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease. Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn's disease, ...

Unlike accidental cell death, some cells can actively decide to die through a controlled process. This is called programmed ...

An experimental compound reduced the cell death, inflammation, and organ damage seen with diabetes. Led by NYU Langone Health researchers, a new study in mice showed that a drug candidate prevented ...

A new study published in Stem Cell Reports demonstrates how a human stem cell-derived model of the intestine can be used to identify potential therapies for inflammatory bowel disease (IBD), ...

When pathogens enter our cells as part of an infection, our body will trigger a programmed cell death known as "pyroptosis" as part of an antimicrobial response. This response also plays a role in ...

(L) Corresponding author Thirumala-Devi Kanneganti, PhD, St. Jude Center of Excellence for Innate Immunity and Inflammation director and Department of Immunology vice chair and (R) and first author ...

Traumatic brain injury (TBI) affects millions of people worldwide every year and remains a major cause of long-term disability, cognitive decline, and neurological complications.

Understanding inflammation – and above all, how to regulate it – is one of the great medical challenges of modern medicine.

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease. Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn’s disease, ...