An international research team has discovered a previously unknown mechanism that plays a key role in the signaling pathways involved in programmed cell death. The team identified the protein HERC4 as ...

Cholesterol, a fat-like substance in the body best known for its role in cardiovascular health, also plays a key role in how ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

A pan-cancer single-cell atlas of nearly 900,000 cells shows that bone metastases from ten cancer types share convergent ...

A protein known as p53 is, of all tumor suppressors in human cancer, the most frequently altered by gene mutations.

Scientists engineered stem cell-derived vesicles to deliver tumor-suppressive miR-124 into colorectal cancer cells, silencing ...

Epithelial cells form the body's frontline barriers, helping keep microbes, toxins and other harmful substances out. Yet these protective cells are constantly exposed to threats, including microbial ...

Blood stem cells are rare cells in the bone marrow that produce the blood and immune cells needed throughout life, thus ensuring that the blood and ...

When a person falls and gets a cut or a scrape, they often use hydrogen peroxide to clean the wound. This molecular compound ...