The membrane that surrounds cells in living organisms is extremely flexible and sensitive. How it protects itself from damage and renews itself is crucial for many life processes, and is not yet fully ...
Cryo-electron microscopy (cryo-EM) has become a powerful tool for determining the structures of proteins, viruses and molecular complexes at near-atomic resolution. However, achievable resolution is ...
Back in 2008, the California NanoSystems Institute at UCLA, or CNSI, debuted a one-of-a-kind resource for understanding biology at the smallest scales — a state-of-the-art cryo-electron microscope. By ...
Time-course cryo-electron microscopy has revealed the sequence of structural changes by which DPP4 receptor binding ...
Cryo-electron microscopy has revealed the first structure of a TenpIN type III toxin-antitoxin complex common to several ...
Collaboration between researchers at the University of Geneva, Institut de biologie structurale de Grenoble, and the University of Fribourg has shown how lipids and proteins in cell membranes react in ...
The enzyme RNA polymerase (RNAP) carries out transcription, copying DNA into RNA. It's the first step in gene expression, and a process fundamental to all life. But the inner workings of this ...
In conjunction with the Structural Biology Core Facility, CEMIL enables practitioners of Cryo-EM within MSK laboratories to design innovative experiments and collect the highest quality Cryo-EM data ...
Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...
From paints and inks to catalysts and drug-delivery materials, many advanced technologies rely on substances dispersed in organic solvents. Yet directly observing these materials in their native ...