Retrospective longitudinal cohort study in infants admitted to United States children’s hospitals. We identified diuretic exposures and measured enteral NaCl and KCl use during pre-defined exposure ...

Start i.v. loop diuretics in the emergency department or clinic setting for significant fluid overload (class I, level B). The initial i.v. dose should equal or exceed the long-term oral daily dose.

Finerenone reduced heart failure events and cardiovascular deaths in patients with HFmrEF or HFpEF when used with diuretics. The study found finerenone reduced hypokalemia risk but increased ...