A prospective case-control study finds that pregnant women with hyperemesis gravidarum have significantly lower circulating ...

4-Phenylbutyrate (4-PBA), a chemical chaperone known to reduce endoplasmic reticulum (ER) stress—a key contributor to kidney injury and fibrosis—has shown therapeutic potential in various disease ...

Cryo-EM structures reveal that the ER membrane protein complex and the Spf1 ATPase form a conserved supercomplex that ...

A new review in Cold Spring Harbor Perspectives in Biology from the Lippincott-Schwartz Lab at HHMI's Janelia Research Campus examines the diverse endoplasmic reticulum structures that have been ...

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these added golden years are not spent in good health. Aging is a natural part of ...

The endoplasmic reticulum is the protein-making factory within cells consisting of tightly stacked sheets of membrane studded with the molecules that make proteins. Now, researchers have refined a new ...

How these shapes arise, however, is largely a mystery. Harvard Medical School cell biologists have now cracked the code for part of the endoplasmic reticulum (ER), a protein - and fat-making organelle ...