A multi-institutional team of researchers led by Case Western Reserve University has identified a pattern of clustered genetic changes that appear to encourage growth of colorectal cancer tumors—a ...

Researchers at the Weill Institute for Cell and Molecular Biology have uncovered new evidence that two major types of gene-controlling DNA sequences, promoters and enhancers, operate with a shared ...

In part 2 of this webinar, Dr. Emily Hodges, assistant professor of biochemistry at Vanderbilt University, will reveal new data that illustrates how the Hodges Lab is utilizing the 6-base genome to ...

Conceptual illustration showing how high transcriptional activity driven by super-enhancers can lead to DNA breaks at oncogenes. When these breaks are repaired inaccurately, they can give rise to ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...