Researchers have identified 15-PGDH enzyme inhibition as a neuroprotective strategy in Parkinson's disease, with repurposable ...

Researchers at Karolinska Institutet and Lund University in Sweden have identified a new treatment strategy for neuroblastoma, an aggressive form of childhood cancer. By combining two antioxidant ...

A new method developed by researchers at KAIST and Chungnam National University could drastically streamline drug interaction testing—replacing dozens of traditional experiments with just one. The ...

Using computational tools and virtual screening, researchers at the Center for Redox Processes in Biomedicine (Redoxoma) have identified new inhibitors of the enzyme human 15-lipoxygenase-2 (h15-LOX-2 ...

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

Capillary electrophoresis (CE) has emerged as a versatile and high‐resolution analytical technique for enzyme kinetics and inhibitor screening. By harnessing narrow‐bore capillaries under high‐voltage ...

Lymphomas belong to the group of malignant diseases of the immune system and mainly affect the organs of the lymphatic system. Anaplastic large cell lymphoma (ALCL) belongs to the subgroup of ...

Grapefruit juice is more than a breakfast staple — it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...

Inhibiting the immune enzyme 15-PGDH protected against neuroinflammation in Parkinson’s disease (PD) models. As 15-PGDH ...