Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

The effects of disease-associated genetic variants on gene expression and genome accessibility have been analysed together.

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

Researchers combined single nucleus RNA-sequencing with GWAS and UK Biobank data to show that an obesity-linked variant in ...

Researchers have identified patterns of gene activity associated with severe COVID-19 in children that are shared with other ...

Researchers have identified patterns of gene activity associated with severe COVID-19 in children that are shared with other ...

Origin-recognition complex (ORC) plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports. "This is the first detailed study ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated ...

From Gene Expression Regulation to Understanding PathophysiologyIntroductionWhile genetic factors contribute strongly to the ...

Researchers at Shanxi Agricultural University have mapped the expression of the gibberellin-deactivating gene CsGA2ox2 across ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation ...