“You’re on a chemotherapeutic and your oncologist may say that your dosage is X, while a nephrologist is telling you that the proximal tubules in your kidneys can’t handle it. You’re harming them.” ...

In a study published in Science, USC researchers paired a biological discovery with an engineering feat to create more ...

Scientists at the University of Southern California have engineered synthetic organiser cells that produce localised Wnt ...

Synthetic organizers provide a way to control formation of kidney organoids as more reliable models for studying disease and ...

MDI Bio Lab scientists discovered how zebrafish solve a basic challenge in regenerative biology—insights in their newest publication in the journal Development could one day guide human repair. When ...

Nephron development in mammals involves a coordinated series of cellular and molecular events that convert undifferentiated progenitors into the functional filtering units of the kidney. The process ...

A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life. Scientists have been studying Wnt actions for four decades to comprehend its ...

In videos created by the Hughes Lab to visualize the process, adjacent nephrons form one after the other, as if they were following a beat. “It’s still a hypothesis,” adds Hughes, “but we think that ...

A pair of USC Stem Cell mouse studies detail how progenitor cells self-renew, differentiate, and aggregate into early kidney structures, offering insights for the creation of stem cell-based ...

The kidney carries out important functions via microscopic functional units called nephrons. Researchers are investigating which factors control the formation and function of specific segments of the ...