Smoking is one of the biggest contributors to lung cancer, but anywhere from 10-20% of cases in the U.S. each year are diagnosed in people who never smoked. In a new study published in Science, ...

C EGFR T790M gene variant face roughly 25 times the lung cancer risk of noncarriers, according to the largest-yet study of the variant. People with ance ...

Non‑smokers with high‑risk traits show up to 32.3% prevalence of germline pathogenic variants in DNA repair genes ...

A genetic mutation that raises lung cancer risk was much more common among those born in Southeastern states than elsewhere ...

The gene is found predominantly in Southern Appalachia and may be one of the most powerful cancer-risk mutations ever found.

A multicenter real-world study found that first-line trastuzumab deruxtecan doubled progression-free survival compared with ...

For decades, society has viewed lung cancer through a singular, judgmental lens: It is the “smoker’s disease.” But a ...

A Phase 3 trial of firmonertinib did not meet its main goal in a hard-to-treat lung cancer subtype, though the drug caused ...

A rare inherited EGFR mutation raises lung cancer odds 25-fold overall and more than 60-fold in never-smokers, revealing why ...

One rare inherited mutation raised lung cancer risk more than smoking did, and the effect was strongest in people who never smoked.

Researchers from several major U.S. universities and ITMO University in Russia have identified a number of new driver mutations in lung cancer cells that may be responsive to genomically targeted ...