Researchers have revealed the structure and function of a previously unknown lysosome transporter. The groups of Christian Löw (CSSB, EMBL Hamburg), Markus Damme (Christian-Albrechts-University Kiel), ...

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged organelles, and unwanted molecules using powerful digestive enzymes. Lysosomes ...

Because the STING protein has multiple functional regions spanning the cell membrane, the researchers did additional experiments to determine which region might be responsible for lysosome generation.

Researchers found that the body’s natural recycling system, the lysosome, plays a vital role in removing the protein that drives premature aging. When this system breaks down, aging speeds up. By ...

Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes. An organelle is a small structure in a cell that is ...

Lysosomes require tight regulation of their pH to degrade their contents. Researchers know that V-ATPase pumps protons into these little digestive sacs, but what protein shuttles the ions back out?

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the immune system. St. Jude Children's Research Hospital scientists recently ...

For the first time, the pathway through which cells repair damaged lysosomes has been observed and described. Lysosomes are the recycling center of a cell, where molecular waste is degraded into the ...

Lysosomes are organelles that play essential roles in cellular digestion and waste management, and lysosomal dysfunction typically leads to serious diseases. In a recent study, scientists developed a ...

Long recognized as the cell’s recycling depot, a new study has found lysosomes act as signaling hubs that coordinate metabolism and longevity by communicating signals across tissues. According to a ...