The Detroit Lions (2-2) and Arizona Cardinals (1-3) clash on Sunday in Week 5 in Glendale, Arizona. Kickoff from State Farm Stadium is at 4:25 p.m. ET (FOX). Let's analyze NFL odds around the Lions vs. Cardinals odds and make our expert NFL picks and predictions for the best bets.

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The Baltimore Ravens and Atlanta Falcons meet Sunday night in Atlanta, Georgia, for a Week 5 battle. Kickoff is slated for 8:20 p.m. ET.

The New England Patriots host the Las Vegas Raiders Sunday in the early slate with a 1 p.m. ET kickoff from Gillette Stadium in Foxborough, Massachusetts.

The Titans Wire staff offer their picks and predictions ahead of a Week 5 game between the Tennessee Titans and Houston Texans.

Cowboys vs. Buccaneers prediction markets feature three Thursday Night Football picks, plus a $55 Kalshi bonus.

The Denver Broncos and Los Angeles Chargers clash on Sunday in Week 5 at 4:05 p.m. ET in Inglewood, California.

Monday Night Football could be the game of the week when the Buffalo Bills (3-1) and Los Angeles Rams (2-2) meet at SoFi Stadium. Buffalo is coming off their first loss of the season versus the Patriots (29-26),