The incidence of chronic pain is estimated to be 20–25% worldwide. Few patients with chronic pain obtain complete relief from the drugs that are currently available, and more than half report ...

Pain and itch are distinct sensations arousing evasion and compulsive desire for scratching, respectively. It’s unclear whether they could invoke different neural networks in the brain. Here, we use ...

Skin shields our bodies from the world’s dangers, but sometimes, with a nick or a bump, that barrier is breached. That’s when pain- and itch-sensing nociceptor neurons jump to action, transmitting ...