Several image-based biomedical diagnoses require high-resolution imaging capabilities at large spatial scales. However, conventional microscopes exhibit an inherent trade-off between depth-of-field ...

We present the Schmidt objective, a novel astronomy-inspired concept for designing multi-immersion microscope objectives with high numerical aperture, long working distance and large field of view.

Pathological analysis has been the gold standard of disease detection, especially in tumor diagnosis. Traditional digital pathology relies on high-precision movement of a high numerical aperture (NA) ...

A project at the University of Colorado Boulder (CU Boulder) has developed a new way to image neural activity in live animals. Described in Biomedical Optics Express, the device is a miniaturized ...

Stereo microscopes are often the first choice when high-quality 3D perception of samples is required in the lab or an industrial facility. Users will frequently spend hours looking through the ...

a, An axi-symmetric binary phase filter (BPF) and image reconstruction network are jointly learned through the physics-informed neural network. The learned BPF is fabricated and inserted in a pupil ...