How cells dodge death: Newly identified protein regulator could reshape cancer treatment

Our bodies are constantly deciding which cells should live and which should die through a process called apoptosis. This type ...
Medical Xpress

Scientists aim to repair or replace p53 to combat cancer

Cancer arises when your cells grow uncontrollably and refuse to die when they should. Normally, your body is equipped with regulatory processes to prevent this chaos. One such mechanism involves a ...
BioWorld

From p53 loss to cancer, a series of unfortunate events

The development of cancer after p53 inactivation is determined by a series of genomic changes that occur in four steps. The loss of heterozygosity of TP53 (the gene encoding p53 in humans, named Trp53 ...
Medical Xpress

Common p53 genetic mutation reveals Achilles' heel in lung cancer

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...