New cell research shows prolonged tadalafil exposure boosts proliferation of muscle progenitor cells, suppresses myostatin ...

A spinal reflex and the L-arginine–nitric oxide–guanylyl cyclase–cyclic guanosine monophosphate (cGMP) pathway mediate smooth muscle relaxation that results in penile erection. Nerves and endothelial ...

Phosphodiesterase 5 (PDE5) inhibitors are a type of drug that can affect blood flow and how cells communicate in the body. PDE5 inhibitors can also appear in some foods and supplements. Share on ...

Please provide your email address to receive an email when new articles are posted on . In a comparison of two erectile dysfunction medications in men with stable CAD, phosphodiesterase type 5, or ...

The phosphodiesterase type-5 (PDE5) inhibitors sildenafil, vardenafil and tadalafil are widely used first-line therapy for erectile dysfunction (ED). Since the advent of sildenafil in 1998, more than ...

BOSTON — In a preliminary study of men with type 2 diabetes, the use of phosphodiesterase type-5 (PDE5) inhibitors was associated with reduced all-cause mortality, even in men who had a previous ...

Please provide your email address to receive an email when new articles are posted on . Patients with pulmonary arterial hypertension at intermediate risk who switched from phosphodiesterase type 5 ...

SAN FRANCISCO, CA—Phosphodiesterase 5 (PDE5) inhibitors appear to be effective in treating Raynaud’s phenomenon secondary to scleroderma, investigators concluded at the 2015 ACR/ARHP Annual Meeting.

Researchers suggested that potency enhancing phosphodiesterase-5 inhibitor drugs may have the ability to improve a prognosis in patients with colorectal cancer. A study published in Nature ...

Some erectile dysfunction (ED) treatments could be beneficial for a person recovering from a heart attack because they help lower blood pressure. However, people should wait 24–48 hours to take ...