Study details how nutrient-starved cells divert protein transport stations to cellular recycling centers to be broken down, highlighting a novel approach cells use to deal with stressful conditions. A ...

The Abu-Remaileh Lab published an atlas of proteins, found in lysosomes across different brain cell types, to advance research on neurodegenerative diseases.

Janelia researchers have uncovered a novel way that two of the structures inside cells—the endoplasmic reticulum (ER) and lysosomes—coordinate the production of proteins, highlighting how interactions ...

Prof. Scott Emr, molecular biology, earned the 2021 Shaw Prize for Life Science and Medicine for unpacking the secrets of a set of proteins that are able to detect key molecular signals to transport ...

Janelia researchers have uncovered a novel way that two of the structures inside cells-the endoplasmic reticulum (ER) and lysosomes-coordinate the production of proteins, highlighting how interactions ...

Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids out of lysosomes, cellular organelles that are the breakdown ...

Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells’ digestive systems by getting rid of unwanted materials. Now in a groundbreaking study, ...

Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular sanitation machines responsible for those tasks, called lysosomes, break ...

Enhanced FIB-SEM images of untreated cells and cells treated with Torin, which causes nutrient stress. The ER exit sites (magenta), ER (blue), mitochondria (green), and all lysosome-related organelles ...