The design of cereblon-binding molecular glues (MGs) that selectively recruit a desired protein while excluding teratogenic SALL4 is an area of significant interest when designing therapeutic agents.
The importance of the insulator-metal transition (IMT) in compressed nickel monoxide (NiO) for the physics of strongly correlated electronic systems ranks close to the problems of insulator-metal ...
Multicolored 3D rendering of a muscle fiber. It looks a bit like a bundle of yarn, with lots of short, aligned strands. A 3D rendering of the proteins in a muscle fiber, captured by cryo-electron ...
Researchers report the first structural confirmation that endogenous -- or self-made -- molecules can set off innate immunity in mammals via a pair of immune cell proteins called the TLR4-MD-2 ...
With the growing demand for resilient, efficient, and low carbon infrastructure, increasing attention has been directed toward novel materials and ...