Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

Researchers have made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides. Mistakes in ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During mitosis, centromeres serve as assembly sites for complex protein ...

Inside each human cell, about 2 meters (6.6 feet) of genomic DNA must be accurately copied and equally transmitted to two daughter cells during cell division. To achieve this, the copied DNA is ...

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

"Every single cell can have a different chromosome structure," Cheng, a Curators' Distinguished Professor of Electrical Engineering and Computer Science, said. "Our tool helps scientists study those ...

A new Nature Communications study reveals how the common AML mutation NPM1c+ exploits failures in mitotic chromosome ...

Super-resolution microscopy image of a mitotic chromosome (white) with the centromeres of each sister chromatid depicted in orange. Each centromere consists of two distinct chromatin subdomains ...