Lung cancer is the most common cancer and the leading cause of overall cancer deaths worldwide. 1 Non-small cell lung cancer (NSCLC) comprises more than 80% of lung cancer. Despite there being great ...

Sodium iodide symporter (NIS)-based radionuclide therapy provides an effective means of treating malignant tumors. However, it is sometimes inadequate and its effects on radio-resistant tumors are ...

Healthy cells have a built-in self-destruct mechanism: Strands of DNA called "telomeres" act as protective caps on the ends of your chromosomes. Each time a cell replicates, telomeres get a little ...

A small-molecule compound named TAC has been identified that reawakens the catalytic subunit of telomerase (TERT) in somatic cells and, in doing so, stalls multiple hallmarks of natural aging without ...

Telomerase reverse transcriptase (TERT), an enzyme associated with nearly all malignant human cancers, is even more diverse and unconventional than previously realized, new CU Boulder research finds.