The Target ALS Global Natural History Study (GNHS) is entering a new phase of discovery. As the only international, ...
ALS is a disease of the motor neurons. However, emerging research from Target ALS-funded scientists is revealing that it’s not that simple; there’s a complex breakdown involving the immune system, ...
Read on for updates across the Research we Enable Postmortem Tissue (PMT) Core The Target ALS Postmortem Core has now ...
Predicting Phenoconversion in Carriers of ALS Pathogenic Variants People carrying mutations known to cause ALS make up at ...
Invested in Biomarker Innovation ALS is a heterogeneous disease with distinct subpopulations of cases clustering together based on common underlying biology and with distinct differences in the ...
In 2011, Dr. Rosa Rademakers (VIB) and her team first identified the repeat expansion mutation in C9orf72 as a major genetic driver of ALS and FTD. However, since this breakthrough, scientists have ...
Antisense Oligonucleotide Tofersen Distribution in the Central Nervous System of SOD1-ALS Autopsy Tissue Donors. Guise AJ, Sellon MT, Roemer SF, Monine M, Comfort Harris NT, […] Plowey ED. JAMA Neurol ...
Artificial intelligence and machine learning now enable the rapid virtual design and testing of thousands of new molecules and the simulation of their interactions with therapeutic targets. Leading ...
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