Idiopathic normal-pressure hydrocephalus is a neurologic disorder characterized by impaired gait, balance, cognition, and ...

Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups. This approach ...

Mayo Clinic researchers have developed a new way to predict whether existing drugs could be repurposed to treat heart failure ...

Icotrokinra is a first-in-class oral peptide drug that selectively inhibits the IL-23 receptor, disrupting IL-23 signaling ...

Many of the randomized controlled trials for large vessel vasculitis with significant or nonsignificant outcomes show fragility, and measures do not vary with the risk for bias, drug type, or subtype.

Automated insulin delivery (AID) systems have been shown to be beneficial for patients with type 1 diabetes, but data are needed from randomized, controlled trials regarding their role in the ...

Results of a new study support using semaglutide and tirzepatide to reduce risk in patients with cardiometabolic heart ...

A Swedish-led research team at Karolinska Institutet and Karolinska University Hospital has shown in a new randomized ...

The CORE-MD (Coordinating Research and Evidence for high-risk Medical Devices) consortium has published new consensus ...

Oral minoxidil at a 2.5 mg daily dose is as effective as 5 mg for androgenetic alopecia in men, with fewer adverse events and ...

The first international trial of an unproven stroke treatment available in the U.S. has concluded that, while harmless, "perispinal" etanercept—injected into the spinal area—is no more effective than ...