By freezing a crucial phosphoric acid complex to near absolute zero, scientists uncovered a single, unexpectedly stable structure at the heart of proton transport.

Biomolecular condensates were long believed to be simple liquid blobs inside cells. Researchers have now uncovered that some are actually supported by fine protein filaments forming an internal ...

Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes.

Cells rely on biomolecular condensates to coordinate essential biological processes without surrounding membranes. These droplet-like dynamic assemblies control the way in which DNA is turned into ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

Tau proteins act like the brain's maintenance crew, helping maintain the structure and proper function of brain cells. In ...

The cerebral cortex, the brain’s outermost region responsible for higher cognitive functions, depends on a highly ordered, ...

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians ...

Opus Genetics targets inherited retinal diseases with one-dose AAV gene augmentations. Read why IRD stock is a Buy.

All cells need to sense and respond to their environment—to know when to activate genes, build proteins and carry out their basic functions. One of the most well-studied cellular responses is how they ...

The left panel depicts a potential-like landscape, where white streamlines represent the inferred trajectory of cell states across time. Although single-cell RNA sequencing captures only static ...

Background Intrahepatic cholangiocarcinoma (iCCA) is a highly aggressive biliary tract cancer with a poor prognosis and a complex tumour microenvironment (TME) that remains poorly understood.