Fragile X disorders include two distinct conditions: fragile X syndrome (the most common single-gene cause of developmental ...

As her patients near the end of life, an infectious disease physician who knows their stories sometimes needs to step out of her proverbial lane to help them assess and achieve their goals of care.

A 64-year-old man presented with a 5-month history of a painful ulcer of the lateral left ankle. Recently, he had noticed malodorous secretions, increased erythema and edema, and worsening pain.

In 2006, a prospective observational study first showed that physical activity after a colon cancer diagnosis was linked to a decreased risk of recurrence and death.1 Since then, numerous observati ...

Allogeneic peripheral-blood stem-cell transplantation (SCT) from a matched related donor after myeloablative conditioning is the preferred curative treatment for patients with high-risk blood cance ...

Use of some antifungal pesticides may select for resistant fungi in the environment, which can then endanger human health. Coordinated regulatory processes in this area are important.

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 21).

Among women with a history of early breast cancer treated with endocrine therapy (tamoxifen or aromatase inhibitors), vasomotor symptoms are common, occurring in up to 90% of this population, and o ...

Pulmonary nodules are detected in more than 1.5 million U.S. residents every year. Nodules are identified incidentally on at least 20% of all diagnostic chest computed tomographic (CT) scans and ar ...

Musunuru and colleagues1 describe in the Journal an innovative approach in which gene editing is applied in the treatment of a very rare disease, the severe urea-cycle disorder carbamoyl-phosphate ...

Among patients with COPD, those with persistent or newly formed mucus plugs at 5-year follow-up had a greater decrease in lung function than those with resolved or no mucus plugs.

New AI-based software for generating patient notes purposely filters out social “chitchat,” but a primary care physician sees serious risks in that practice, for doctors and patients alike.